Professional topical care
The U.S. Rejuran Professional line includes topical formulas such as Healing Essence, Healing Essence i, Skin Booster, and Tone-Up Booster. Product selection depends on your skin and the protocol available at Muse.
Rejuran® Professional · Bellevue
Recovery-minded
skin renewal.
A professional topical protocol featuring Hydrolyzed DNA refined with patented Korean DOT™ technology—selected to support hydrated, soothed, healthy-looking skin.
U.S. professional products · topical use onlyRejuran Professional products sold in the United States are not injectable drug products.
An important distinction
What it is.
What it isn’t.
Not injectable Rejuran
Products sold by Rejuran in the United States are intended for topical application only. Muse does not present this service as injectable PN, a filler, or an FDA-approved injectable treatment.
The formulation story
DOT™ technology,
made for topical care.
Rejuran’s patented DNA Fragments Optimizing Technology refines Hydrolyzed DNA from wild chum salmon for use in its professional skincare formulas.
According to Rejuran Professional, these formulations are designed to support the skin’s moisture barrier and improve the visible appearance of dryness, texture, fine lines, redness, and uneven tone. We treat those statements as cosmetic product claims—not as promises to diagnose, prevent, or treat disease.
- Hydration and barrier-focused support
- Professional, post-procedure topical options
- Eye-area and tone-focused formulas available within the line
Ingredient source matters: tell your provider about fish, salmon, or marine-product sensitivities before treatment.
FORMULATION / 01
DOT™Patented refining technologyINGREDIENT / 02
2%Hydrolyzed DNA in Healing Essence, as listed by the manufacturerAPPLICATION / 03
TopicalProfessional use in the United StatesDesigned around skin quality
A considered layer
in your treatment plan.
Rejuran Professional may be selected when the goal is to support the look and feel of skin—not to add volume or change facial structure.
Dehydrated or compromised-looking skin
Visible redness after an appropriate procedure
Dull, uneven-looking tone
Fine lines and rough texture
Delicate under-eye skin
Barrier-conscious post-procedure care
The Muse protocol
Personalized from
consultation to aftercare.
Rejuran Professional is not a one-size-fits-all add-on. We decide whether it belongs in your plan only after reviewing the procedure, your skin barrier, sensitivities, and recovery priorities.
Consult
We review your skin, current routine, sensitivities, treatment history, and the result you want to see.
Customize
Your provider determines whether a Rejuran Professional topical product fits the visit and how it should be paired with your treatment plan.
Apply
The selected professional formula is applied topically according to the manufacturer’s U.S. protocol—never injected.
Support
You leave with individualized aftercare guidance, including when to resume active skincare and how to protect the skin barrier.
TOPICAL
USE ONLY
USE ONLY
Clear, responsible care
No ambiguity about how Rejuran is used.
The official U.S. Rejuran Professional website states that its U.S. products are not drug products, are intended for topical use only, and are not intended to prevent, treat, or cure diseases or medical conditions. Muse follows that positioning on this page and in consultation.
Common questions
Before your
visit.
Is Rejuran injected at Muse MedSpa?+
No. The Rejuran Professional products described on this page are the U.S. professional line and are used topically only. The U.S. manufacturer states that any non-topical use of its products is not authorized in the United States.
What is DOT™ Hydrolyzed DNA?+
Rejuran describes DOT™ as its patented refining process for producing high-purity Hydrolyzed DNA from a marine source. In the U.S. professional line, Hydrolyzed DNA is used as a topical cosmetic ingredient in formulas designed to support hydrated, calm, healthy-looking skin.
When might a provider recommend it?+
A provider may consider a Rejuran Professional topical formula as part of a customized skin-quality or post-procedure protocol. The exact pairing depends on the treatment, skin condition, sensitivities, and products available at Muse.
Is it appropriate for the under-eye area?+
The professional line includes Healing Essence i, a topical formula created for delicate eye-area skin. Suitability still requires an in-person assessment, and it is not an injectable filler or a substitute for medical treatment.
How many visits will I need?+
There is no universal schedule. Some people use Rejuran Professional as a single post-procedure topical step, while others may be advised to follow a series or home-care plan. Your provider will recommend timing after evaluating your skin and goals.
Who should discuss extra precautions?+
Tell us about known fish or marine-source sensitivities, active irritation, infection, pregnancy or nursing, medications, and recent procedures. A patch test or a different protocol may be more appropriate for some patients.
Reviewed sources
Official U.S.
product information.
Rejuran Professional — U.S. official website Rejuran Professional — DOT™ and Hydrolyzed DNA science Rejuran Professional — Healing Essence product and protocol
Source review updated October 19, 2026. Manufacturer information is provided for education and does not replace an individualized medical assessment. Individual experiences vary.
Bellevue · Seattle Eastside
Build a calmer,
smarter recovery plan.
Meet with the Muse team to discuss your skin, treatment timing, sensitivities, and whether a Rejuran Professional topical protocol belongs in your plan.
Book a consultation